{"id":8850,"date":"2023-06-08T09:29:40","date_gmt":"2023-06-08T09:29:40","guid":{"rendered":"https:\/\/www.healthnews.ie\/?p=8850"},"modified":"2023-06-19T07:44:09","modified_gmt":"2023-06-19T07:44:09","slug":"enabling-personalised-medicine-for-cancer-patients-across-the-island-through-digital-revolution","status":"publish","type":"post","link":"https:\/\/www.healthnews.ie\/oncology\/enabling-personalised-medicine-for-cancer-patients-across-the-island-through-digital-revolution\/","title":{"rendered":"Enabling personalised medicine for cancer patients across the island through digital revolution"},"content":{"rendered":"\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"274\" height=\"273\" class=\"ab-profile-avatar wp-image-8851\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/624w596h-walter-kolch.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/624w596h-walter-kolch.jpg 274w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/624w596h-walter-kolch-125x125.jpg 125w\" sizes=\"auto, (max-width: 274px) 100vw, 274px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Prof Walter Kolch<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Director of Systems Biology Ireland, based at <a href=\"https:\/\/www.ucd.ie\/sbi\/\" target=\"_blank\" rel=\"noreferrer noopener\">UCD<\/a><\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n\n\n\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box right round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" class=\"ab-profile-avatar wp-image-8852\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/1-William_Gallagher_UCD.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/1-William_Gallagher_UCD.jpg 400w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210338\/1-William_Gallagher_UCD-125x125.jpg 125w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Prof William Gallagher<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Full Professor of Cancer Biology at UCD, <br\/>Co-Lead of the <a href=\"https:\/\/www.aicri.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">All-Island Cancer Research Institute<\/a><\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n\n\n\n<p><em>Biology and medicine are morphing into data-driven sciences. The dream of personalised medicine \u2014 finding the right medicine for the right patient at the right time \u2014 is coming into reach.&nbsp;<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<p>This <a href=\"https:\/\/www.ucd.ie\/research\/\" target=\"_blank\" rel=\"noreferrer noopener\">digital transformation<\/a> is particularly visible in oncology, where genome sequencing in the clinic has shown the importance of data analysis in enabling clinical decision-making, and the development of computational models that allow us to interact with and do bespoke analyses of data.&nbsp;&nbsp;<\/p>\n\n\n\n<p>At the leading edge, cancer researchers at <a href=\"https:\/\/www.ucd.ie\/research\/\" target=\"_blank\" rel=\"noreferrer noopener\">UCD<\/a> have received strategic investment in key interdisciplinary projects covering fundamental biomedical science to computational biology, data science and AI. &nbsp;<\/p>\n\n\n<div id=\"healt-3239414105\"><div class=\"healt-adlabel\">Advertisements<\/div><div id=\"healt-2517385695\" style=\"margin-top: 30px;margin-bottom: 30px;margin-left: auto;margin-right: auto;text-align: center;\"><a data-no-instant=\"1\" href=\"https:\/\/www.ucd.ie\/research\/\" rel=\"noopener\" class=\"a2t-link\" target=\"_blank\" aria-label=\"UCD desk\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210332\/UCD-desk.jpg\" alt=\"\"  width=\"750\" height=\"250\"  style=\"display: inline-block;\" \/><\/a><\/div><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"h-using-the-power-of-data-for-personalised-medicine\"><strong>Using the power of data for personalised medicine<\/strong>&nbsp;<\/h2>\n\n\n\n<p>UCD-based research centre Systems Biology Ireland (SBI), led by international leader in personalised medicine Prof Walter Kolch, is leading the charge towards clinical adoption of digital twin models (DTMs) in cancer treatment.&nbsp;&nbsp;<\/p>\n\n\n\n<p>SBI\u2019s approach is to analyse computer models of patients and understand every individual\u2019s tumour, enabling the design of the best therapeutic intervention via computer simulation. \u201cThe goal is for real cancer patients to receive the optimum treatment \u2014 the treatment most likely to work on their cancer with fewer harmful side effects,\u201d says Prof Kolch.&nbsp;&nbsp;<\/p>\n\n\n\n<p>This endeavour has been boosted by national investment in groundbreaking consortium Precision Oncology Ireland, led by SBI, which unites the efforts of five universities and associated hospitals, six cancer charities and seven industry partners.&nbsp;<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>As a community, we need to overcome narrow, <br>single institution mindsets so we can build <br>sufficient critical mass, inclusively.<\/p><\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Leveraging research networks<\/strong>&nbsp;<\/h2>\n\n\n\n<p>UCD\u2019s Professor William Gallagher co-leads the All-Island Cancer Research Institute (AICRI), which \u2014 together with colleagues in the US and Europe \u2014 is building a global collaborative network to evolve the <a href=\"https:\/\/www.ucd.ie\/research\/\" target=\"_blank\" rel=\"noreferrer noopener\">research and innovation<\/a> (R&amp;I) ecosystem in cancer research.&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u201cAs a community, we need to overcome narrow, single institution mindsets so we can build sufficient critical mass, inclusively \u2014 to gain a better understanding of cancer and develop more personalised treatment options to ease suffering and save lives,\u201d explains Professor Gallagher. &nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center\"><a href=\"https:\/\/www.ucd.ie\/research\/\" target=\"_blank\" rel=\"noreferrer noopener\">Making fundamental discoveries with real, far-reaching impact for people and our planet.<\/a><\/p>\n\n\n\n<p>This virtual institute, involving 10 academic institutions and linked clinical centres, provides an overarching framework for cancer research from discovery to implementation across the island of Ireland \u2014 where one in two people will develop cancer during their lifetime.&nbsp;<\/p>\n\n\n\n<p>So far, AICRI has attracted funding to pursue \u2018compelling ideas\u2019 from the cancer research community in the areas of personalised cancer medicine, liquid biopsies and eHealth, including a doctoral and post-doctoral training programme in personalised cancer medicine called AICRIstart.&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u201cThis project will<em> <\/em>train the next generation of cancer researchers in cutting-edge scientific approaches, with an emphasis on inter-institutional collaboration,\u201d concludes Professor Gallagher. \u201cAICRIstart will provide a roadmap of even greater collaboration.\u201d&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210316\/Fluorescent-staining-of-different-immune-cell-types-in-breast-cancer-tissues.jpg\" alt=\"\" class=\"wp-image-9036\" width=\"379\" height=\"389\"\/><\/figure><\/div>\n\n\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><body><div style=\"text-align:center\" class=\"wp-block-atomic-blocks-ab-button ab-block-button\"><a href=\"https:\/\/www.ucd.ie\/research\/spotlights\/cancer\/innovationsinoncologyfeaturewithaicriandsbi\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"ab-button ab-button-shape-rounded ab-button-size-medium fb-pixel\" style=\"color:#ffffff;background-color:#0289cd\">Click here to learn more<\/a><\/div>\n<\/body><\/html>\n","protected":false},"excerpt":{"rendered":"<p>Biology and medicine are morphing into data-driven sciences. The dream of personalised medicine \u2014 finding the right medicine for the right patient at the right time \u2014 is coming into reach.&nbsp; This digital transformation is particularly visible in oncology, where genome sequencing in the clinic has shown the importance of data analysis in enabling clinical &hellip; <a href=\"https:\/\/www.healthnews.ie\/oncology\/enabling-personalised-medicine-for-cancer-patients-across-the-island-through-digital-revolution\/\">Continued<\/a><\/p>\n","protected":false},"author":91,"featured_media":8862,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2856],"tags":[5816],"class_list":["post-8850","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oncology","tag-innovations-in-oncology-q2-2023"],"acf":[],"featured_image_src":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210335\/GettyImages-697650898-600x400.jpg","featured_image_src_square":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/06\/07210335\/GettyImages-697650898-600x600.jpg","author_info":{"display_name":"henryphillips","author_link":"https:\/\/www.healthnews.ie\/author\/henryphillips\/"},"vicky_index_order":"","_links":{"self":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/users\/91"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/comments?post=8850"}],"version-history":[{"count":11,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8850\/revisions"}],"predecessor-version":[{"id":9051,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8850\/revisions\/9051"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media\/8862"}],"wp:attachment":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media?parent=8850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/categories?post=8850"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/tags?post=8850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}