{"id":8012,"date":"2023-02-20T15:02:09","date_gmt":"2023-02-20T15:02:09","guid":{"rendered":"https:\/\/www.healthnews.ie\/?p=8012"},"modified":"2023-03-02T09:59:55","modified_gmt":"2023-03-02T09:59:55","slug":"recognising-hereditary-attr-amyloidosis-early-can-improve-your-quality-of-life","status":"publish","type":"post","link":"https:\/\/www.healthnews.ie\/rare-diseases\/recognising-hereditary-attr-amyloidosis-early-can-improve-your-quality-of-life\/","title":{"rendered":"Recognising hereditary ATTR amyloidosis early can improve your quality of life"},"content":{"rendered":"\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"250\" height=\"250\" class=\"ab-profile-avatar wp-image-8013\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/02\/07210504\/Rosaline-pic_.png\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/02\/07210504\/Rosaline-pic_.png 250w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/02\/07210504\/Rosaline-pic_-125x125.png 125w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Rosaline Callaghan<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Founder, ATTR Amyloidosis All Ireland Support Group and Northern Ireland representative on the All Ireland Rare Diseases Steering Committee<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n\n\n\n<p><em>Genetic testing and screening are available for this serious, debilitating and sometimes fatal hereditary disease, <a href=\"https:\/\/www.hattr-amyloidosis.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">hATTR amyloidosis<\/a>.<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<p>Rosaline Callaghan, a retired Barrister living in Derry, learnt that she carried the gene mutation that causes&nbsp; hereditary ATTR amyloidosis, in 2007. At that time, she was told that finding a treatment for this fatal disease was unlikely.&nbsp;<\/p>\n\n\n\n<p>\u201cI saw my father die of this,\u201d says Rosaline. \u201chATTR relentlessly affects your organs and nervous system.\u201d Rosaline left work at 53 to travel, wanting to make the most of her time while she was in good health, having developed her own personal plan for the future, should the disease progress.&nbsp;<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>hATTR relentlessly affects your <br>organs and nervous system.<\/p><\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-early-signs\"><strong>Early signs<\/strong><\/h2>\n\n\n\n<p>While travelling in Turkey in 2018, she developed arm and wrist pain overnight. \u201cI knew it was a sign,\u201d she says. Later, she developed pins and needles and reduced feeling in her feet. She returned home to Derry, and following investigation, it was confirmed that she had hATTR amyloidosis. <\/p>\n\n\n\n<p>\u201cMy particular genetic mutation, T80A, originates from Northwest Donegal, so anyone genetically linked to that area should know about this \u2014 so should GPs and wrist surgeons, as Carpal Tunnel Syndrome can be an early sign,\u201d she warns.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Get tested for hATTR<\/strong><\/h2>\n\n\n\n<p>Now, Rosaline raises awareness of hATTR amyloidosis, alongside Amyloidosis Ireland and Rare Diseases Ireland. She informs and urges people: \u201cToday, treatment, <a href=\"https:\/\/www.hattr-amyloidosis.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">genetic testing and family screening are available<\/a>. If you suspect you may have hATTR amyloidosis, get tested now.\u201d&nbsp;<\/p>\n\n\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><body><div style=\"text-align:center\" class=\"wp-block-atomic-blocks-ab-button ab-block-button\"><a href=\"https:\/\/www.hattr-amyloidosis.org\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"ab-button ab-button-shape-rounded ab-button-size-medium fb-pixel\" style=\"color:#ffffff;background-color:#003162\">Click here to learn more<\/a><\/div>\n<\/body><\/html>\n\n\n\n<p class=\"has-text-align-right\" style=\"font-size:11px\">DS- UK \u2013 00003 , Feb 2023<br><meta charset=\"utf-8\"><em>Alnylam are the sole sponsors of this content only. They nominated the two interviewees and reviewed all content prior to publication.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Genetic testing and screening are available for this serious, debilitating and sometimes fatal hereditary disease, hATTR amyloidosis. Rosaline Callaghan, a retired Barrister living in Derry, learnt that she carried the gene mutation that causes&nbsp; hereditary ATTR amyloidosis, in 2007. At that time, she was told that finding a treatment for this fatal disease was unlikely.&nbsp; &hellip; <a href=\"https:\/\/www.healthnews.ie\/rare-diseases\/recognising-hereditary-attr-amyloidosis-early-can-improve-your-quality-of-life\/\">Continued<\/a><\/p>\n","protected":false},"author":108,"featured_media":8014,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5778],"tags":[5779],"class_list":["post-8012","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rare-diseases","tag-rare-diseases-q1-2023"],"acf":[],"featured_image_src":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/02\/07210503\/GettyImages-1012405368-600x400.png","featured_image_src_square":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2023\/02\/07210503\/GettyImages-1012405368-600x600.png","author_info":{"display_name":"Carolina Galbraith Duarte","author_link":"https:\/\/www.healthnews.ie\/author\/carolinagalbraithduarte\/"},"vicky_index_order":"","_links":{"self":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/users\/108"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/comments?post=8012"}],"version-history":[{"count":16,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8012\/revisions"}],"predecessor-version":[{"id":8283,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/8012\/revisions\/8283"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media\/8014"}],"wp:attachment":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media?parent=8012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/categories?post=8012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/tags?post=8012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}