{"id":12069,"date":"2024-11-27T12:09:38","date_gmt":"2024-11-27T12:09:38","guid":{"rendered":"https:\/\/www.healthnews.ie\/?p=12069"},"modified":"2024-12-13T08:44:54","modified_gmt":"2024-12-13T08:44:54","slug":"experts-in-respiratory-medicine-are-driving-research-and-innovation-with-global-impact","status":"publish","type":"post","link":"https:\/\/www.healthnews.ie\/respiratory\/experts-in-respiratory-medicine-are-driving-research-and-innovation-with-global-impact\/","title":{"rendered":"Experts in respiratory medicine are driving research and innovation with global impact"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" class=\"ab-profile-avatar wp-image-12104\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/09155634\/Costello-RW-2023.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/09155634\/Costello-RW-2023.jpg 400w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/09155634\/Costello-RW-2023-125x125.jpg 125w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Richard Costello<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Professor of Respiratory Medicine at the RCSI, and Consultant Respiratory Physician at Beaumont Hospital<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" class=\"ab-profile-avatar wp-image-12070\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120044\/8-Killian-Hurley.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120044\/8-Killian-Hurley.jpg 400w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120044\/8-Killian-Hurley-125x125.jpg 125w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Killian Hurley<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Associate Professor at RCSI, and Consultant Respiratory Physician at Beaumont Hospital<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"206\" height=\"206\" class=\"ab-profile-avatar wp-image-12091\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/03162042\/Prof-Mc-003.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/03162042\/Prof-Mc-003.jpg 206w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/03162042\/Prof-Mc-003-125x125.jpg 125w\" sizes=\"auto, (max-width: 206px) 100vw, 206px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Gerry McElvaney<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Professor of Medicine, and Head of the Department of Medicine and Respiratory Research Division at Beaumont Hospital<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" class=\"ab-profile-avatar wp-image-12072\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120148\/4-Professor-Gerard-Curley-1.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120148\/4-Professor-Gerard-Curley-1.jpg 400w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120148\/4-Professor-Gerard-Curley-1-125x125.jpg 125w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Gerard Curley<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Professor of Anaesthesia and Critical Care at the RCSI, and Consultant in Anaesthesia and Intensive Care at Beaumont Hospital<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<p><em>The collaborative efforts of experts in anaesthesia, critical care and respiratory medicine are leading groundbreaking discoveries, driving innovation and improving patient outcomes.<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>Seeking commercialisation to bring technological advances into clinical practice, Professor of Respiratory Medicine Richard Costello discusses his innovative approach to the management of asthma, which affects around 1 in 13 people in Ireland alone. \u201cThere is no simple test for asthma, and we typically still use traditional testing methods \u2014 but our understanding is more advanced now,\u201d he says.<\/p>\n\n\n\n<p>\u201cWe are using the strengths of new digital technologies for home monitoring, which enables us to see the lived experience of the patient, including their response to treatment,\u201d he adds. \u201cThrough the use of digital technology, we reduce the cost of prescribing by 60%, but we need more funding to bring this technology into practice.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-award-winning-respiratory-health-discoveries\"><strong>Award-winning respiratory health discoveries <\/strong><strong><\/strong><\/h2>\n\n\n\n<p>Professor of Medicine Gerry McElvaney\u2019s work has been instrumental in advancing the <a href=\"https:\/\/www.rcsi.com\/dublin\/research-and-innovation\/research\/resources-and-facilities\/clinical-research-centre\" target=\"_blank\" rel=\"noreferrer noopener\">understanding and treatment<\/a> of respiratory diseases, such as cystic fibrosis and alpha-1 antitrypsin (AAT) deficiency. His team\u2019s work on genetic therapies, particularly altering the faulty genes responsible for severe forms of AAT deficiency, has been not only groundbreaking but award-winning.<\/p>\n\n\n\n<p>\u201cAs a direct result of our discoveries, we have spearheaded the national targeted detection programme for alpha-1 antitrypsin deficiency, providing free diagnostics for individuals with chronic obstructive pulmonary disease (COPD), asthma or unexplained liver disease,\u201d cites McElvaney. \u201cThe potential to cure diseases rather than merely alleviate symptoms is within reach, but we need more support for sophisticated clinical trials. We need the government to look at areas of excellence and support them if we are to integrate key developments into our health system.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-key-innovations-in-critical-care\"><strong>Key innovations in critical care <\/strong><strong><\/strong><\/h2>\n\n\n\n<p>Making considerable progress in key areas of critical care medicine, Professor of Anaesthesia and Critical Care Gerard Curley is focusing efforts on acute respiratory distress syndrome (ARDS), a condition affecting approximately 10% of all patients admitted to the ICU. \u201cThis condition has a high mortality burden, and survivors tend to have neurocognitive and physical disabilities,\u201d explains Curley. \u201cUnfortunately, there is no magic bullet for the condition, and current treatment remains supportive.\u201d<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>You can\u2019t take new technology and <br>discoveries into clinics without <br>first asking: does this work?<\/p>\n<\/blockquote>\n\n\n\n<p>He adds: \u201cOur primary focus is on the <a href=\"https:\/\/www.rcsi.com\/dublin\/research-and-innovation\/research\/resources-and-facilities\/clinical-research-centre\" target=\"_blank\" rel=\"noreferrer noopener\">development of therapies<\/a>, particularly through the use of translational medicine or \u2018bench to bedside\u2019 approaches, which use a detailed study of patients to identify characteristics that might better predict responses to specific therapies. These precision medicine strategies will help to improve patient outcomes. We&#8217;re exploring alpha-1 antitrypsin as a potential treatment in specific cohorts of patients with ARDS, leveraging ex vivo lung perfusion models to test and refine therapies.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-focusing-on-pulmonary-fibrosis\"><strong>Focusing on pulmonary fibrosis <\/strong><strong><\/strong><\/h2>\n\n\n\n<p>Focusing on the genetic and molecular complexities of pulmonary fibrosis, Consultant Respiratory Physician Killian Hurley discusses his work, exploring why some families are genetically predisposed to the condition in an attempt to shape potential treatment approaches. \u201cThese patients have an extremely poor prognosis, and new treatments typically work to slow disease progression rather than cure the disease,\u201d says Hurley.<\/p>\n\n\n\n<p>\u201cWorking closely with patients and patient advocacy groups, our primary goal is to find new, less toxic treatments, which could significantly improve patient outcomes\u201d he adds. \u201cFor patients with pulmonary fibrosis, a comprehensive national care programme is essential if they are to access the support they need. This type of national approach could coordinate efforts in research and treatment development and facilitate the advancement of potential new therapies.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-maintaining-high-standards-of-respiratory-research\"><strong>Maintaining high standards of respiratory research<\/strong><\/h2>\n\n\n\n<p>None of this would be possible without the <a href=\"https:\/\/www.rcsi.com\/dublin\/research-and-innovation\/research\/resources-and-facilities\/clinical-research-centre\" target=\"_blank\" rel=\"noreferrer noopener\">RCSI Clinical Research Centre<\/a>, which provides the facilities and expertise needed for investigators to conduct clinical research to the highest standard. \u201cYou can\u2019t take new technology and discoveries into clinics without first asking: does this work? The clinical research centre is helping us to generate the proof,\u201d insists Costello.<\/p>\n\n\n\n<p>\u201cThe experienced nurses, administrators and trial experts add immeasurable value.\u201d As McElvaney aptly describes in one of his many expert TED talks: \u2019Lung disease has Ireland fighting for breath,\u2019 but with the help of the RCSI Clinical Research Centre, there is real hope.<\/p>\n\n\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><body><div style=\"text-align:center\" class=\"wp-block-atomic-blocks-ab-button ab-block-button\"><a href=\"https:\/\/www.rcsi.com\/dublin\/research-and-innovation\/research\/resources-and-facilities\/clinical-research-centre\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"ab-button ab-button-shape-rounded ab-button-size-medium fb-pixel\" style=\"color:#ffffff;background-color:#d11333\">Click here to learn more<\/a><\/div>\n<\/body><\/html>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The collaborative efforts of experts in anaesthesia, critical care and respiratory medicine are leading groundbreaking discoveries, driving innovation and improving patient outcomes. Seeking commercialisation to bring technological advances into clinical practice, Professor of Respiratory Medicine Richard Costello discusses his innovative approach to the management of asthma, which affects around 1 in 13 people in Ireland &hellip; <a href=\"https:\/\/www.healthnews.ie\/respiratory\/experts-in-respiratory-medicine-are-driving-research-and-innovation-with-global-impact\/\">Continued<\/a><\/p>\n","protected":false},"author":91,"featured_media":12075,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[130],"tags":[5957],"class_list":["post-12069","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-respiratory","tag-respiratory-health-2024"],"acf":[],"featured_image_src":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120744\/RCSI-0881-600x400.jpg","featured_image_src_square":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/11\/27120744\/RCSI-0881-600x600.jpg","author_info":{"display_name":"henryphillips","author_link":"https:\/\/www.healthnews.ie\/author\/henryphillips\/"},"vicky_index_order":"","_links":{"self":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/12069","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/users\/91"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/comments?post=12069"}],"version-history":[{"count":6,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/12069\/revisions"}],"predecessor-version":[{"id":12110,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/12069\/revisions\/12110"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media\/12075"}],"wp:attachment":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media?parent=12069"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/categories?post=12069"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/tags?post=12069"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}