{"id":11519,"date":"2024-06-20T17:15:28","date_gmt":"2024-06-20T17:15:28","guid":{"rendered":"https:\/\/www.healthnews.ie\/?p=11519"},"modified":"2024-06-24T08:10:44","modified_gmt":"2024-06-24T08:10:44","slug":"navigating-europes-genomic-landscape-to-drive-progress-in-personalised-medicine","status":"publish","type":"post","link":"https:\/\/www.healthnews.ie\/life-sciences\/navigating-europes-genomic-landscape-to-drive-progress-in-personalised-medicine\/","title":{"rendered":"Navigating Europe\u2019s genomic landscape to drive progress in personalised medicine"},"content":{"rendered":"\n<div style=\"background-color:#f2f2f2;color:#32373c\" class=\"wp-block-atomic-blocks-ab-profile-box round ab-has-avatar ab-font-size-14 ab-block-profile ab-profile-columns\"><div class=\"ab-profile-column ab-profile-avatar-wrap\"><div class=\"ab-profile-image-wrap\"><figure class=\"ab-profile-image-square\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" class=\"ab-profile-avatar wp-image-11564\" src=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/06\/07205739\/Elaine-Murray.jpg\" alt=\"\" srcset=\"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/06\/07205739\/Elaine-Murray.jpg 400w, https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/06\/07205739\/Elaine-Murray-125x125.jpg 125w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure><\/div><\/div><div class=\"ab-profile-column ab-profile-content-wrap\"><h2 class=\"ab-profile-name\" style=\"color:#32373c\">Elaine Murray<\/h2><p class=\"ab-profile-title\" style=\"color:#32373c\">Public Affairs Lead, EIT Health Ireland &#8211; UK<\/p><div class=\"ab-profile-text\"><\/div><ul class=\"ab-social-links\"><\/ul><\/div><\/div>\n\n\n\n<p><em>Healthcare is evolving due to patient expectations, digital transformation and scientific research. New delivery models, such as personalised medicine through genomics, could enhance cost efficiencies, diagnoses and predictability in care.<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>By studying an individual\u2019s complete set of genetic material (genome), researchers can determine why people have varying disease risks and why medicines affect them differently. With this information, the right therapeutic strategy can be tailored for the right person at the right time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-moving-ireland-s-genomic-strategy-forward\"><strong>Moving Ireland\u2019s genomic strategy forward<\/strong><\/h2>\n\n\n\n<p>In 2022, the HSE published its <a href=\"https:\/\/www.hse.ie\/eng\/about\/who\/strategic-programmes-office-overview\/national-strategy-for-accelerating-genetic-and-genomic-medicine-in-ireland\/\" target=\"_blank\" rel=\"noreferrer noopener\">National Strategy<\/a> for Accelerating Genetic and Genomic Medicine in Ireland. However, research based on genomic data generated in Ireland is relatively underdeveloped, with factors contingent on its optimal delivery, such as access to personalised health information.<\/p>\n\n\n\n<p>Impending regulations could be catalysers for change. The European Parliament recently passed a framework to enable cross-border sharing of digital health information, the European Health Data Space. Ireland\u2019s Department of Health published its roadmap to implement a patient app and shared care records as part of \u2018Digital for Care: A Digital Health Framework for Ireland 2024 \u2013 2030.\u2019<\/p>\n\n\n\n<p>System and infrastructure changes are required nationally to drive the genomic strategy. With system overhauls already underway in several European countries to advance genomic innovation, local policymakers and researchers need only look to our neighbours for inspiration and collaboration opportunities.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-personalised-medicine-in-practice\"><strong>Personalised medicine in practice<\/strong><\/h2>\n\n\n\n<p>In Estonia, the passing of the Human Genes Research Act led to the establishment of a Genome Centre. The centre draws data from cancer registries, causes of death registries, electronic health records, health insurance funds, hospital databases and research projects. Over a 20+ year biobanking journey, 20% of Estonia&#8217;s adult population has now had their genetic material genotyped.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>System and infrastructure changes are required nationally to drive the genomic strategy.<\/p>\n<\/blockquote>\n\n\n\n<p>Analyses of gene variants in the genome have contributed to 830+ peer-reviewed papers, leading to advances in scientific research and early disease detection. Today, the Estonian Biobank boasts a 70%+ public approval rating.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-transitioning-to-a-healthcare-landscape-tailored-to-individual-needs\"><strong>Transitioning to a healthcare landscape tailored to individual needs<\/strong><\/h2>\n\n\n\n<p>The European Genomic Data Infrastructure project, backed by \u20ac40 million in funding from the European Commission, brings together 54 partners from across 20 countries, including Ireland, to create technical capacity for accessing genomic data in Europe.<\/p>\n\n\n\n<p>The new European Partnership for Personalised Medicine (<a href=\"https:\/\/www.eppermed.eu\/\" target=\"_blank\" rel=\"noreferrer noopener\">EP PerMed<\/a>), launched under Horizon Europe, has a budget of \u20ac375 million over 10 years. It aims to ensure that the long-term vision of personalised medicine is translated into roadmaps with funding and supporting activities.<\/p>\n\n\n\n<p>Researchers in Ireland can leverage these well-funded European projects to draw on a wider pool of actionable genetic information. International collaboration in genomic research will be pivotal to the discovery of innovative treatments and, ultimately, enhance patient care.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Healthcare is evolving due to patient expectations, digital transformation and scientific research. New delivery models, such as personalised medicine through genomics, could enhance cost efficiencies, diagnoses and predictability in care. By studying an individual\u2019s complete set of genetic material (genome), researchers can determine why people have varying disease risks and why medicines affect them differently. &hellip; <a href=\"https:\/\/www.healthnews.ie\/life-sciences\/navigating-europes-genomic-landscape-to-drive-progress-in-personalised-medicine\/\">Continued<\/a><\/p>\n","protected":false},"author":23,"featured_media":11520,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2216],"tags":[5918],"class_list":["post-11519","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-sciences","tag-life-sciences-q2-2024"],"acf":[],"featured_image_src":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/06\/07205747\/AdobeStock_707051168-600x400.jpg","featured_image_src_square":"https:\/\/s3.eu-north-1.amazonaws.com\/cdn-site.mediaplanet.com\/app\/uploads\/sites\/94\/2024\/06\/07205747\/AdobeStock_707051168-600x600.jpg","author_info":{"display_name":"Your Future Career","author_link":"https:\/\/www.healthnews.ie\/author\/harveyodonnell\/"},"vicky_index_order":"","_links":{"self":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/11519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/comments?post=11519"}],"version-history":[{"count":2,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/11519\/revisions"}],"predecessor-version":[{"id":11565,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/posts\/11519\/revisions\/11565"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media\/11520"}],"wp:attachment":[{"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/media?parent=11519"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/categories?post=11519"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthnews.ie\/wp-json\/wp\/v2\/tags?post=11519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}